The age of animal experiments is waning. Where will science go next?

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Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing diverse regulatory mechanisms shaping complex traits and disease.

"I noticed that the brick was a very pink-cast brick, and it had a little bit of a charcoal overlay on it. It was a modular eight-inch brick and it was square-edged," he says. "When I saw that, I knew exactly what the brick was," he adds.

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